The quality of evidence for comparisons of these treatments was low (in other words the findings may be true but are likely to change with more clinical data.) There were no randomized trials for several commonly used treatments such as expressing (poking!) lesions with an orange stick or topical hydrogen peroxide. The other studies considered a variety of comparisons of treatment including cryospray (this is a freezing treatment), 10% Australian lemon myrtle oil, 10% benzoyl peroxide, 0.05% tretinoin, 5% sodium nitrite, 5% salicylic acid, tea tree oil and several others. Together with another published trial, these studies contributed nearly half of the participants (about 800 in all) and compared 5% imiquimod cream to placebo (a dummy cream). Three of the studies included were unpublished (2005) and had been undertaken by 3M Pharmaceuticals, and submitted to the American Food and Drug Association. Most of the participants were children or young adults.The review considered clinical cure in the short, medium and long term, as well as short term improvement and adverse effects. 20 of these studies looked at topical treatments and two looked at systemic treatments. The review authors aimed to assess the effectiveness of various treatment and management strategies for cutaneous (ie on the skin, but excluding the genital areas) molluscum contagiosum in people whose immunity was not compromised.Īre there effective treatments for molluscum contagiosum?Ĭochrane reviews are periodically updated and there were 11 new studies to add since the previous version, making 22 in total, involving 1650 participants. In May 2017 the Cochrane systematic review Interventions for cutaneous molluscum contagiosum was published. Let’s take a look at what the Cochrane Review has to say
This advice is based on what CKS considers to be good clinical practice in UK. pulsed dye laser, phenol ablation, imiquimod 5%, cantharidin, potassium hydroxide 10%, podophyllin, silver nitrate paste, benzoyl peroxide 10%, and retinoids).
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Treatments listed in the 2012 NICE CKS (Clinical Knowledge Summaries) for the management of molluscum contagiosum include the following recommendations : This aimed to remove the central core, which harboured the virus. When I was a newly qualified GP (35 years ago…oh dear) one popular treatment was to poke out the centre of the spot with an orange stick. How can molluscum contagiosum be treated? If traumatised the spots may bleed slightly. They do not usually cause symptoms unless inflamed or infected when they can become painful or itchy. The spots sometimes heal leaving a scar, especially if they have been traumatised or become infected. If the spots are extensive and/or highly visible they can cause significant psychological distress because of their cosmetic appearance. On the whole, the spots clear within 6-18 months but they can last for several years. The infection most commonly resolves over time but it can be doggedly persistent. What problems can molluscum contagiosum virus cause? Molluscum contagiosum is more common and often more extensive in people with atopic eczema and people whose immune system is suppressed, for example by HIV infection or immunosuppressant medication, may develop large numbers of spots. The virus can also be spread by scratching or picking at the spots. It can also be transmitted by clothes, towels, toys etc which have been in contact with the virus. MCV is highly contagious, in other words it is spread from person to person by touching affected skin. How do we catch molluscum contagiosum virus? This file is licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license.
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